Iranian Tissue Engineering and Regenerative Medicine (ITERM)

Bone grafting is a big business
, generating sales of more than $2.5 billion a year.1 Of the more than 3 million musculoskeletal procedures done annually in the United States, about half involve bone grafting with either an autograft or an allograft.2 Worldwide, autografts or allografts are used in approximately 2.2 million orthopaedic procedures annually3.

References:
 Desai BM: Osteobiologics. Am J Orthop 2007;36:8-11.
US Centers for Disease Control and Prevention: ttp://www.cdc.gov/ncidod/dhqp/tissueTransplantsFAQ.html#d
Giannoudis PV, Dinopoulos H, Tsiridis E: Bone substitutes: An update. Injury 2005Nov;36: S20-S27.